List of accepted talks
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Cancer
Chair: Marina Mione
5th July (Wednesday) 11:00-12:30
A non-canonical function of telomerase RNA in myelopoiesis
Jesús Garcia-Castillo, Francisca Alcaraz-Pérez, Diana García Moreno, Manuel Bernabe-Garcia, Elena Martinez-Balsalobre, Ana B. Perez-Oliva, Victoriano Mulero, Maria L. Cayuela
A preclinical zebrafish model of brain tumor with alternative mechanisms of telomere maintenance (ALT)
Aurora Idilli, Marialuisa Cayuela, Marina Mione
Accurate Quantification of Homologous Recombination in Zebrafish: brca2 deficiency as a paradigm
Jeroen Vierstraete, Y. Willaert, Petra Vermassen, Leen Pieters, Paul J. Coucke, Anne Vral, Kathleen B.M. Claes
Cell lineage tracing revealed the reversion of liver tumor cells to normal hepatocytes during tumor regression of xmrk transgenic zebrafish
Yan Li, Zhiyuan Gong
Estrogen sensing in the liver by the G protein-coupled receptor GPER1 regulates PI3K/AKT and MTOR activity to control normal and malignant growth
S. Chaturantabut, A. Cox, K. Evason, A. Schepers, D. Gorelick, S. Bhatia, T.E. North, Wolfram Goessling
Extravascular Migratory Metastasis and Angiotropism in Uveal and Cutaneous Melanoma Progression
Giulia Fornabaio, R. Barnhill, C. Lugassy, S. Roman-Roman, S. Alsafadi, F. Del Bene
Modeling BRIP1/FANCJ DNA helicase overexpression in a dβh-MYCN neuroblastoma zebrafish model supports its role as cooperative 17q driver oncogene involved in G-quadruplex induced replicative stress
Suzanne Vanhauwaert, A. Fieuw, C. Leonelli, E. Janssens, B. Decaesteker, J. De Wyn, P. Depuydt, S. De Brouwer, Neuroblastoma Research Consortium, N. Van Roy, S. He, A.T. Look, K. de Preter, F. Speleman,
Chemical biology
Chair: Philipp Gut
3rd July (Monday) 17:00-18:30
A small molecule screen identifies candidate compounds restoring ILK-dependent signaling in an in-vivo model of genetic cardiomyopathy
Maryam Shahid, D. Köhler, C. Pylatiuk, W. Rottbauer and Steffen Just
In vivo drug discovery identifies a compound that reduces seizure-like activity in the zebrafish model of CLN2 disease
R. Martin-Jimenez, F. Mahmood, V. Brickell, D. Nalkos, M. Campanella, Claire Russell
Inhibition of Cdk5 Promotes β-cell Differentiation from Ductal Progenitors in Zebrafish and Mouse/Human Stem Cells
Ka-Cheuk Liu, Daisuke Sakano, Charlotte L. Mattsson, Linn Rautio, Shoen Kume, Olov Andersson
M3 muscarinic receptors limit pacemaker potential during early cardiogenesis
Martina S. Burczyk, Martin D. Burkhalter, Teresa Casar Tena, Laurel A. Grisanti, Sabrina Matysik, Sebastian Wiese, Monika Kustermann, Melanie Rothe, Michael Kühl, Wolfram H. Zimmermann, Juergen Wess, Douglas G. Tilley, Melanie Philipp
Synthetic reconstruction of nodal signaling through genetic code expansion
Saravanan Palani, Junetha Syed, Scott Clarke, Shruthi Vijaykumar, Leo Vong, Andreas Zaucker, Mohan Balasubramanian, Karuna Sampath
The role of the tumor suppressor Lkb1 in metabolic adaptation
Laurie A. Mans and A-P. Haramis
Chi-Bin Chien Award
PAPP-AA regulates photoreceptor synaptogenesis to mediate dark elicited behavior
Andrew Miller, Holly Howe, Scott Friedle, Marc Wolman
Circuits and behaviour
Chair: Harold Burgess
6th July (Thursday) 14:00-16:00
Expressing acetylcholine receptors after innervation suppresses spontaneous vesicle release and causes muscle fatigue
Fumihito Ono, Meghan Mott, Victor M. Luna, Jee-Young Park, Gerald B. Downes, Kimberly Epley
Light-sheet based whole-brain neuronal activity recording during vestibular stimulation
Volker Bormuth
Motile-cilia-mediated flow improves sensitivity and temporal resolution of olfactory computations
Ingrid Reiten, Fazil Emre Uslu, Stephanie Fore, Robbrecht Pelgrims, Christa Ringers, Carmen Diaz Verdugo, Maximillian Hoffman Pradeep Lal, Koichi Kawakami, Kerem Pekkan, Emre Yaksi and Nathalie Jurisch-Yaksi
Neurotransmitter switching in oxytocin neurons is associated with a long-term effect on social behavior
Janna Blechman, E. Wircer, N. Borodovsky, M. Tsoory, A.R. Nunes, R.F. Oliveira, G. Levkowitz
Novel hypophysiotropic AgRP2 neurons and pineal cells revealed by BAC transgenesis in zebrafish
Inbal Shainer and Yoav Gothilf
Social recognition and fear buffering in zebrafish
Ajay S. Mathuru, Annett Schirmer, Ng Phui Yeng Tabitha, Caroline Kibat, Ruey-Kuang Cheng, Suresh Jesuthasan, Seetha Krishnan
Disease models I
Chair: Rachel Giles
4th July (Tuesday) 09:00-10:30
Extensive regulation of diurnal transcription and metabolism by glucocorticoids
Benjamin D. Weger, Meltem Weger, Benjamin Görling, Andrea Schink, Cédric Gobet, Teoman Akcay, Céline Keime, Gernot Poschet, Bernard Jost, Rüdiger Hell, Nils Krone, Tülay Güran, Frédéric Gachon, Burkhard Luy and Thomas Dickmeis
From structure to function: an in vivo, in vitro and in silico analysis of the dyskerin enzyme
Máté Varga, György Ferenczy, Gusztáv Schay, Dóra K. Menyhárd, Eszter Balogh, Dóra Judit Kiss, Renáta Hamar, Regina Légrádi and Kálmán Tory
Loss of erythropoietin aggravates hyperglycemia induced renal damage and alters embryonic renal development via induction of apoptosis in zebrafish
Jianqing She and Jens Kroll
Mutant ush2a zebrafish models show early onset retinal dysfunction
Margo Dona, R. Slijkerman, T. Peters, L. Hetterschijt, H. Kremer, S.C. Neuhauss, J. Zang, M. Kamermans, M. Westerfield, J.B. Phillips and E. van Wijk,
The Undiagnosed Diseases Network: Validation of YPEL3 as a disease causing gene
Bernardo Blanco-Sánchez, Aurélie Clément, Jennifer Phillips, Jeremy Wegner, Judy Peirce and Monte Westerfield
Therapeutic drug discovery and development using a zebrafish genetic model of Dravet syndrome
Aliesha L. Griffin, K.R. Hamling, K. Knupp, P. Jaishankar, A.R.Renslo and S.C. Baraban
Disease models II
Chair: Monte Westerfield
4th July (Tuesday) 11:00-12:30
A model to measure tau protein clearance in vivo – investigating how the A152T-tau variant contributes to multiple neurodegenerative diseases
Ana Lopez Ramirez, S. E. Lee, G. Coppola, B. L. Miller, D. C. Rubinsztein, A. Fleming
Cilia formation is coupled to mitochondrial homeostasis
Martin D. Burkhalter, Martina S. Burczyk, Competence Network for Congenital Heart Defects Investigators, Dorota Wloga, Paul Walther, Melanie Philipp
Deciphering the function and mechanisms of C9ORF72 in ALS
Hortense de Calbiac, Sorana Ciura, Maria-Letizia Campanari, Doris-Lou Demy, Nicolas Charlet-Berguerand, Edor Kabashi
Generalized light-induced seizures in gabra1 knockout zebrafish: a simple model for unravelling the molecular basis of epilepsy and screening for anti-epileptic drugs
Éric Samarut, Raphaëlle Riché, Amrutha Swaminathan, Meijiang Liao and Pierre Drapeau
Phenomics analysis of zebrafish type I collagen mutants reveals a spectrum of skeletal phenotypes mimicking the clinical variability in human brittle bone disease
A. Willaert, C. Gistelinck, R.Y. Kwon, F. Malfait, P. Vermassen, H. De Saffel, K. Henke, M. Weis, A. De Paepe, M. P. Harris, D. R. Eyre, P. J. Coucke
Zebrafish Thyroid: a model to investigate Physio-Pathological Implications of the H2O2-generating System
N. Giusti, R. Opitz, A. Trubiroha, P. Gillotay, F. Miot, S. Costagliola and Xavier De Deken
Disease models III
Chair: Yann Gibert
4th July (Tuesday) 16:00-17:30
A zebrafish model of classic galactosemia: paving the way for new insights on this metabolic disorder
A.I. Coelho, J.M. Vanoevelen, B. van Erven, J. Bierau, X. Huang, G.T. Berry, R. Vos, M.E. Rubio-Gozalbo,
Dynamics of mitochondrial biogenesis in zebrafish skeletal muscle
Alice Parisi, Laura Strohm, Joy Richard, Eugenia Migliavacca, Jerome Feige, Bruce M. Spiegelman, Philipp Gut
Na+/K+-ATPase is an essential regulator of the vertebrate heart rate
Alexander Pott, Sarah Bock, Karin Frese, Tillman Dahme, Mirjam Kessler, Nils Decher, Wolfgang Rottbauer, Steffen Just
Regulation of the feeding-to-fasting transition by the tumor suppressor LKB1
Laurie A. Mans, Laia Querol Cano, Jason van Pelt, Panagiota Giardoglou, Willem-Jan Keune and Anna-Pavlina G. Haramis
Zebrafish Model of Saethre-Chotzen Syndrome Reveals Genetic Conservation Despite Shifts in Tissue Origins
Camilla Teng, Robert Maxson, Gage Crump
Genetic disruption of 21-hydroxylase in zebrafish causes interrenal hyperplasia – an in vivo model for congenital adrenal hyperplasia
Helen Eachus, A. Zaucker, A. Griffin, K. Storbeck, T. Güran, M. Weger, A. Taylor, F. Mueller, N. Krone
Education
Chair: Daria Goś
3rd July (Monday) 11:15-12:00
Drinking like a fish: A locally relevant, enquiry-based zebrafish development practical to enhance engagement and relevance in a very large, diverse class of beginning university life sciences students
Kate Hammond
e-ZFbook, a new teaching concept
Peter Aleström, Charles M. Press, Michael Moulton, Håkon Sverdvik, Erik M.K. Rasmussen, Elisabeth Dyb, Runa Malmo
Earn your stripes – planning and delivering a successful zebrafish outreach activity
Claire Allen, Claire Wilkinson
Emerging technologies I
Chair: Tatjana Sauka-Spengler
6th July (Thursday) 09:00- 10:30
A novel Biotagging approach uncovers a complex world of non-coding regulatory RNAs in the nuclear transcriptome that specify migratory neural crest identity
Vanessa M. R. Chong,, Le A. Trinh, , Daria Gavriouchkina, Tatiana Hochgreb-Hagele, Upeka Senanayake, Scott E. Fraser, Tatjana Sauka-Spengler
Automated deep-phenotyping of the zebrafish brain
A. Allalou, Y. Wu, M. Ghannad-Rezaie, P.M. Eimon, Mehmet Fatih Yanik
Mapping vertebrate differentiation hierarchies with high-throughput single-cell transcriptomics
Daniel E. Wagner, Sean Megason, Allon Klein
Morphometric phenomics and Cross-Atlas Registration of Virtual 3D soft tissue microCT images of Zebrafish
Keith C. Cheng, Y. Ding, A.Y. Lin, M. Yakovlev, D. Vanselow, X. Xin, S. Katz, D. van Rossum, P.J. La Riviere
Single-cell analysis of cell specification and lineage
Alex Schier
Emerging technologies II
Chair: Ferenc Müller and Máté Varga
6th July (Thursday) 11:00-12:
A New Framework for Interactive Knowledge Discovery in Large-Scale Trajectory Data of Zebrafish Embryos
B. Schott, M. Traub, T. Antritter, C. Schlagenhauf, M. Takamiya, A. Barschat, J. C. Otte, A. Kobitski, G. U. Nienhaus, P. Sanders, U. Strähle, R. Mikut, Johannes Stegmaier
Genome-wide profiling of Scl-expressing cells identifies distinct regulatory programmes underlying formation of hematopoietic and vascular progenitors in vivo
Lucy S. Wheatley, D. Gavriouchkina, R. Rispoli, L.A. Trinh, S.E. Fraser, R. Patient, T. Sauka-Spengler
High-Throughput Screening and Analysis of Startle Response Behavior in Zebrafish
Ravindra Peravali, Daniel Marcato, Johannes Stegmaier, Robert Geisler, Christian Pylatiuk, Markus Reischl, Jos van Wezel, Ralf Mikut, Julia Dallman and Uwe Strähle
In vivo detection and variation of native zygotic transcription of a gene locus in the zebrafish embryo
Yavor Hadzhiev, Ledean Cooper, Haseeb Qureshi, Nan Li, John Fossey, Hui Nguyen, Sacha Conic, György Hutvágner, Attila Sik, Lászlo Tora and Ferenc Müller
Massively parallel single-cell lineage tracing using CRISPR/Cas9 induced genetic scars
Jan Philipp Junker
Light induction of cancer in zebrafish
David Bensimon, Zhiping Feng, Shimon Weiss, Sophie Vriz, Michel Volovitch, Ludovic Jullien, Bertrand Ducos, Fatime Hamouri
Targeting drugs to specific cell layers of the posterior eye segment: implementation of “smart” strategies of ocular neuroprotection in zebrafish model
M. Giannaccini, L. Pedicini, A Usai, L. Dente, Vittoria Raffa
Fish biology and aquaculture
Chair: László Orbán
6th July (Thursday) 11:00-12:30
Aging, Autophagy and Apoptosis in Growth Hormone-Transgenic Zebrafish Larvae
A.K. Elbialy, W. T. Wang, S. Kinoshita, S. Asakawa, S. Watabe
Antigen uptake during different life stages of zebrafish (Danio rerio) using a GFP-tagged Yersinia ruckeri
R. Korbut, F. Mehrdana, P. W. Kania, M. H. Larsen, D. Frees, I. Dalsgaard, L. v. G. Jørgensen
Chemical communication in cichlids and zebrafish
Adelino V.M. Canário
Egg transcriptome reveals molecular signature that can predict developmental competence and novel maternal-effect genes
Caroline T. Cheung, T. Nguyen, A. LeCam, A. Patinote, C. Reynes and J. Bobe
High temperature and rearing density can masculinize domesticated zebrafish: Possible implications for fish farming
Laia Ribas, A. Valdivieso, W.C. Liew, L. Orbán, F. Piferrer
Nothobranchius furzeri: A short-lived killifish as a new model for age research
Kathrin Reichwald andreas Petzold, Philipp Koch, Bryan R. Downie, Nils Hartmann, Mario Baumgart, Hans A. Kestler, Manfred Schartl, Alessandro Cellerino, Matthias Platzer, Christoph Englert
Zebrafish and salmon as complementary models to study the endocrine regulation of testicular gene expression accompanying the initiation of spermatogenesis
Rüdiger W. Schulz, Diego Crespo, Roberto Morais, Diego Safian, Luiz H. de Castro Assis, Rafael Nóbrega, Geir Lasse Taranger, Eva Andersson, Anna Wargelius, Florence Le Gac, Elisabeth Sambroni, Jan Bogerd
Zebrafish intubation as a model to study mucosal immunity: TNFα protein nanoparticles protect zebrafish against a Mycobacterium marinum challenge
Jie Ji, Debora Torrealba, Nerea Roher
Genomics/Epigenetics
Chair: José-Luis Gomez Skarmeta
3rd July (Monday) 17:00-18:00
Epigenomic imprinting of heart development and its perturbations
Michal Pawlak, Katarzyna Kedzierska, Karim Abu Nahia, Hashimoto Kosuke, Jordan Ramilowski, Lukasz Bugajski, Aleksandra Marconi, Katarzyna Piwocka, Piero Carninci, Cecilia Winata,
Generational effects of low dose ionizing radiation on DNA methylation in zebrafish
Jorke H. Kamstra, L.S. Hurem, Martin Martin, L.C. Lindeman, J. Legler, J.L. Lyche, P. Aleström
The establishment of transcriptionally competent chromatin during zebrafish zygotic genome activation
Máté Pálfy, Gunnar Schulze, Eivind Valen, Nadine L. Vastenhouw
Uncovering novel targets for p63-related hereditary malformations
José M. Santos-Pereira and Juan J. Tena
Genomics-Resources Workshop
Chair: Elisabeth Busch-Nentwich
3rd July (Monday) 12:00-13:00
High quality genome assemblies for zebrafish and relatives
Kerstin Howe, William Chow, Joanna Collins, Gregory Concepcion, Sarah Pelan, Michael Quail, Michelle Smith, Glen Threadgold, James Torrance, Jonathan Wood, Shane McCarthy, Jason Chin, Gene Myers, Richard Durbin
A high-resolution mRNA expression time course of embryonic development in zebrafish
Richard J. White, John E. Collins, Ian M. Sealy, Neha Wali, Christopher M. Dooley, Derek L. Stemple, Daniel Murphy, Thibaut Hourlier, Anja Füllgrabe, Matthew P. Davis, Anton J. Enright, Elisabeth Busch Nentwich
DANIO-CODE update
Ferenc Müller
De Novo Assembly of the Zebrafish and Goldfish Genomes Using a Combination of PacBio and 10X Genomics Sequencing Approaches
Zelin Chen, Asao Fujiyama, Hironori Wada, Takuya Shirokiya, Takuo Kuroda, Atsushi Miyamoto, Kevin Bishop, Blake Carrington, Raman Sood, Koichi Kawakami, James C. Mullikin, Yoshihiro Omori, Shawn M. Burgess
Husbandry
Chair: Zoltan Varga
3rd July (Monday) 08:30-09:30
A pneumatic dispenser for fast delivery of fish food
Francesco Argenton and Luigi Pivotti
Different impact of dry feeds on zebrafish growth and reproductive performance
Telma Costa, Joana F. Monteiro, Sandra Martins, Ana C. Certal
Successful elimination of live feeds in a high production zebrafish facility
Carrie L. Barton, L. Truong, R.L. Tanguay
Zebrabase: An intuitive zebrafish tracking database solution
Jana Oltova, J. Jindrich, C. Skuta, O. Svoboda, O. Machonova and P. Bartunek
Immunity and infectious disease
Chair: Annemarie Meijer
5th July (Wednesday) 16:00-17:30
An evolutionarily conserved Ankyrin domain-containing protein regulates inflammasome activation and bacterial clearance
Sylwia D. Tyrkalska, Sergio Candel, Ana B. Pérez-Oliva, Ana Valera, Francisca Alcaraz-Pérez, Diana García Moreno, María L. Cayuela, Victoriano Mulero
Imaging of viral neuroinvasion in the zebrafish reveals that Sindbis and Chikungunya viruses rely on different entry routes
Gabriella Passoni, Christelle Langevin, Nuno Palha, Bryan C. Mounce, Valérie Briolat, Pierre Affaticati, Elodie De Job, Jean-Stéphane Joly, Marco Vignuzzi, Maria-Carla Saleh, Philippe Herbomel, Pierre Boudinot, Jean-Pierre Levraud
Macrophages target Salmonella by Lc3-associated phagocytosis in a systemic infection model
S. Masud, Annemarie H. Meijer
Mycobacteria employ multiple mechanisms to cross the blood-brain barrier
Lisanne M. van Leeuwen, Daisy I. Picavet, Maikel Boot, Gunny van den Brink, Coen Kuijl, Susanne M. A. van der Pol, H. Elga de Vries, Nicole N. van der Wel, Martijn van der Kuip, Marceline A. Tutu-van Furth, Wilbert Bitter and Astrid M. van der Sar
Spore shuttling between leukocytes in zebrafish fungal infection models is driven by components of the fungal cell wall
Vahid Pazhakh, Felix Ellett, Alex Andrianopoulos, Graham J. Lieschke
The role of AhR in innate immune responses to Pseudomonas aeruginosa infection
Pedro Moura-Alves, Andreas Puyskens, Anne Stinn, Annika Kreuchwig, Jens Furkert, Anca Dorhoi, Anne Diehl, Ute Guhlich-Bornhof, Marion Klemm, Robert Hurwitz, Michael Kolbe, Hartmut Oschkinat, Gerd Krause, Stefan H.E. Kaufmann
Neurobiology
Chair: Caren Norden
4th July (Tuesday) 16:00-17:30
A Crispr/Cas9 screen for genes that mediate growth of the zebrafish eye
Leonardo E. Valdivia, J. Plaisancie, L.T. Tucker, M. Khosravi, E.W. Mackay, R. Wycliffe, B. Deml, E.V. Semina, S.W. Wilson
Developing a zebrafish model for investigating neurovascular function
Karishma Chhabria, K. Plant, C. Howarth, P.M. Santoscoy, V.T. Cunliffe, O. Bandmann, T.J.A. Chico
Functional analysis of Meteorin and Meteorin-like proteins in zebrafish neurodevelopment
Flavia De Santis, T. Auer, K. Duroure, F. Del Bene
Insights into the Cellular and Molecular Mechanisms of Microglia Ontogeny
Giuliano Ferrero, Eleonore Dupuis, David Traver, Julien Bertrand, Valerie Wittamer,
Loss of lrrk2 impairs cell proliferation, catecholaminergic catabolism and reactive neurogenesis in the zebrafish brain
Stefano Suzzi, Reiner Ahrendt, Stefan Hans, Saygin Bilican, Shady Sayed, Sandra Spiess, Svetlana Semenova, Pertti Panula, Michael Brand
Splicing factor proline-glutamine rich (SFPQ) in motor axon development and neurodegeneration
Richard Taylor, T. Fielding, P. Gordon & C. Houart
Organogenesis I
Chair: Didier Stainier
5th July (Wednesday) 09:00-10:30
Blood flow and cilia control vascular mural cells recruitment in vertebrates
Massimo Santoro, Xiaowen Chen, Dafne Gays, Carlo Milia
Cells specialize towards growth-promoting or functional roles during organ scaling
Sumeet Pal Singh, Sharan Janjuha, Theresa Hartmann, Özge Kayışoğlu, Sarah Birke, Priyanka Murawala, Kei Murata, Anne Eugster, Naoki Tsuji, Michael Brand, Nikolay Ninov
Essential and Compensatory Functions for GATA Transcription Factors during Zebrafish Organogenesis
E.J. Mercer, I. Torregroza and Todd Evans
Loss of TDP-43 causes angiogenic defects by increasing fibronectin and integrina4/b1
Katrin Strecker, Bettina Pitter, Miha Modic, Sebastian Lewandowski, Alexander Hruscha, Stefan Bonn, Eloi Montanez, Bettina Schmid
Neural crest contribute to the hematopoietic stem cell specification niche
E.W. Damm, M. Ganuza, S. McKinney-Freeman, Wilson K. Clements
Targeted blood vessel deletion through stabilin-dependent nanoparticle uptake in scavenger endothelial cells
Jeroen Bussmann, S. Sieber, F.L. Bos, E. van Rooijen, G.Arias-Alpizar, B.Koch, L.I.Zon, H.Spaink, J. Huwyler, A. Kros and F. Campbell
Organogenesis II
Chair: Olov Andersson
5th July (Wednesday) 11:00-12:30
A CRISPR/Cas-based mutagenesis approach in zebrafish to delineate gene function underlying congenital hypothyroidism
Pierre Gillotay, A. Trubiroha, N. Giusti, B. Haerlingen, D. Gacquer, R. Opitz and Sabine Costagliola
Cardiac lymphatic development in the adult zebrafish
Michael Harrison, Xidi Feng, Stefan Schulte-Merker, Ching-Ling Lien
Close similarity between pancreatic and intestinal endocrine cells as revealed by their transcriptome analysis and the loss of isl1 function
Justine Pirson, David Stern, Arnaud Lavergne, Isabelle Manfroid, Bernard Peers, Marianne L. Voz
Endoglin controls blood vessel diameters via endothelial cell shape changes in response to haemodynamic cues
Wade Sugden, Robert Meissner, Tinri Aegerter-Wilmsen, Roman Tsaryk, Elvin Leonard, Jeroen Bussmann, Mailin Hamm, Wiebke Herzog, Cornelia Denz, Arndt Siekmann
foxc1a and foxc1b exhibit distinct compensatory requirements during brain and trunk angiogenesis and haematopoietic stem cell formation in zebrafish
Zhen Jiang, T. Evans, M. Loose, T.J.A. Chico, R.N. Wilkinson
Ptf1a+, ela3l– cells are developmentally maintained progenitors for exocrine regeneration following extreme loss of acinar cells in zebrafish larvae
Nicole Schmitner, Kenji Kohno, Dirk Meyer
Organogenesis III
Chair: Steve Wilson
5th July (Wednesday) 16:00-17:30
A Novel Endothelium-Derived Perivascular Cell Population in the Zebrafish Brain
Marina Venero Galanternik, Daniel Castranova, Aniket V. Gore, Nathan H. Blewett, Hyun Min Jung, Amber N. Stratman, Martha R. Kirby, Mayumi F. Miller, James Iben, Koichi Kawakami, Richard J. Maraia and Brant M. Weinstein
Aberrant endothelial cell migration and vascular defects due to estrogen excess during developmental angiogenesis
Silvia Parajes, D. Y. Stainier
Cerebral Cavernous Malformation proteins dampen the Klf2a-dependent mechanotransduction during cardiac valve formation
Alessio Paolini, Stefan Donat, Marta Lourenço, Cécile Otten, Marc Renz and Salim Abdelilah-Seyfried
hey2 negatively regulates Second Heart Field progenitor contribution to the zebrafish heart
Natalie L. Gibb, S. Lazic, A. Deshwar, I. C. Scott,
Intracellular uptake of macromolecules by brain lymphatic endothelial cells during embryonic development
Max van Lessen, Shannon Shibata-Germanos andreas van Impel, Thomas A. Hawkins, Jason Rihel and Stefan Schulte-Merker
Role of flow and mechanotransduction during outflow tract valve morphogenesis
Anne-Laure Duchemin, Julien Vermot
Patterning I
Chair: Mary Mullins
4th July (Tuesday) 11:00-12:30
CachD1 is a novel type I transmembrane protein that regulates the development of habenular asymmetry in zebrafish
Ana Faro, H. Stickney, G. Powell, G. Gestri, I. Lekk, P. Henriques, R. Young, T. Hawkins, F. Cavodeassi, Q. Schwartz, G. Wright, D. Raible, S. Wilson
Coordinate Regulation of Development by a Shared RNA Element
Andreas Zaucker, Agnieszka Nagorska, Yin Wang, Sizhou Huang, Ledean Cooper, Pooja Kumari, Nikolai Hecker, Jan Brosens, Jan Gorodkin and Karuna Sampath
Delta/Notch signaling is essential for the establishment of apico-basal polarity in the zebrafish spinal cord
Priyanka Sharma, Vishnu Muraleedharan Saraswathy, Li Xiang, Maximilian Fürthauer
Dishevelled isoforms play distinct function in embryonic patterning and morphogenetic movements during zebrafish early development
Yan-Yi Xing, Ming Shao, De-Li Shi
Self-organizing pattern formation downstream of Nodal required for endoderm specification
Antonius L. van Boxtel, A.D. Economou, C. Heliot, G. Salbreux, S. Grigolon, C.S. Hill
The chromatin factor Udu/Gon4l regulates embryonic axis extension by promoting notochord boundary-associated cell polarity through limiting epcam expression
Margot L.K. Williams, Atsushi Sawada, Terin Budine, Chunyue Yin, Lilianna Solnica-Krezel
Patterning II
Chair: Florence Marlow
5th July (Wednesday) 11:00-12:30
Cell and Tissue Morphogenesis at the interface between the Cerebrospinal Fluid and the Spinal Cord
L.F. Desban, Y. Cantaut-Belarif, A. Prendergast, J. Roussel, J. Sternberg, O. Thouvenin, C. Boccara, C. Wyart, Pierre-Luc Bardet
CRISPR/Cas9 induced mutations in zebrafish CS/DS glycosyltransferase genes – effects on glycosylation, morphology and transcriptome
J. Habicher, G. Varshney, S.M. Burgess, Johan Ledin
Endogenous lipid peroxidation product 9-HSA regulates progenitor fate in the vertebrate retina
Shahad Albadri, F. Naso, C. Parolin, K. Duroure, J. Fiori, C. Boga, N. Calonghi, F. Del Bene
Mechanism of ectopic lens fiber differentiation in response to early endosome trafficking defects
A. Hagiwara, T. Mochizuki, Y. Kojima, Y. Nishiwaki and Ichiro Masai
Nr2f nuclear receptors antagonize Edn1 signaling to specify the upper jaw
Lindsey Barske, Pauline Rataud, Samuel G. Cox, Ruchi Bajpai, J. Gage Crump
The Hippo Pathway effector Taz is required for the formation of the Micropyle in Zebrafish
Chaitanya Dingare, Peng Xia, Luis Ricardo Fuentes, Mary Mullins, Carl-Philipp Heisenberg and Virginie Lecaudey
Reproductive Biology and Evolutionary Biology
Chair: Marie-Andrée Akimenko
5th July (Wednesday) 16:00-17:30
Contributions of 5’HoxA/D regulatory changes to actinodin evolution and fin-to-limb transition
Robert L. Lalonde, A. Bakshi, Y. Kherdjemil, R. Sheth, M. Kmita and M-A. Akimenko
MiR-202 knock-out in medaka drastically impairs female fertility
S. Gay, J. Bugeon, A. Bouchareb, L. Henry, J. Bobe, Violette Thermes
Sequential events mediating germ plasm RNP segregation and multimerization
Celeste Eno, Timothy Gomez, Diane Slusarski, Francisco Pelegri
The RNA-binding protein Rbpms2 is required for female germline development
Odelya H. Kaufman, KathyAnn Lee, Sophie Rothhamel, Lianna Schwartz-Orbach, Darius Balciunas, Bruce W. Draper and Florence L. Marlow,
Zebrafish: A potential model for studies on unusual fish sex
W.C. Liew, S. Vij, J. Jiang, J. M. Saju, N.M. Thevasagayam and László Orbán
ZRS deletion in medaka reveals an ancestral cis-regulatory logic for median and paired appendages in vertebrates
Joaquín Letelier, Elisa de la Calle-Mustienes, Joyce Pieretti, Ignacio Maeso, Silvia Naranjo, Tetsuya Nakamura, Neil Shubin, Igor Schneider, Juan Ramón Martinez Morales and José Luis Gómez-Skarmeta
Resources
Chair: Kiyoshi Naruse
3rd July (Monday) 09:30-10:45
A new, easy and reliable cryopreservation protocol for zebrafish sperm
Sandra Martins, Ana Catarina Certal
Cryogenic Resource Preservation and Inventory Management at the Zebrafish International Resource Center
Zoltán M. Varga
How to make your fish see-through? Pnp4a is the causal gene of the medaka iridophore mutant, guanineless
Kiyoshi Naruse, Tetuaki Kimura, Yusuke Takehana
Introduction of Taiwan Zebrafish Core Facilities
Sheng-Ping. L. Hwang, May-Su. Yu, Yun-Jin Jiang and Chiou-Hwa Yuh
Resource Construction and Technical Services at the China Zebrafish Resource Center (CZRC)
Yonghua Sun, Luyuan Pan, Kuoyu Li, Feng Xiong, Xunwei Xie, Liyue Liu, Linglu Li, Zhang Yun
Signaling
Chair: Karuna Sampath
6th July (Thursday) 11:00-12:30
A Guanine Nucleotide Exchange Factor Activity-independent Function of Nuclear Net1 in Nodal/Smad2 Signaling and Mesendoderm Induction
Shi Wei, Guozhu Ning, Linwei Li, Yifang Yan, Shuyan Yang, Yu Cao, Qiang Wang
A novel bi-directional reporter to monitor the activity of NF-κB signaling in zebrafish in real time
Paola Kuri, Kornelia Ellwanger, Thomas A. Kufer, Maria Leptin, Baubak Bajoghli
Eph receptor signaling in zebrafish erythroid burst cell line
Ondrej Svoboda, Olga Machonova, Jana Oltova, David Traver, Petr Bartunek
Focal activation of Fgf signalling pathway in leading cells promotes collective migration of parapineal organ in the zebrafish brain
L. Wei, F. Kuchling, P. Retaud, M. Tsalavouta, J. Wittbrodt , M.Tsang, M. Carl, S. Wilson, P. Blader , M. Roussigne
Molecular Mechanisms regulating Osteoblast Dedifferentiation during Zebrafish Fin Regeneration
Rashmi Mishra, Ivonne Sehring, Gilbert Weidinger
Scale-invariant patterning by size-dependent inhibition of Nodal signaling
María Almuedo-Castillo, Alexander Bläßle, David Mörsdorf, Luciano Marcon, Katherine W. Rogers, Alexander F. Schier and Patrick Müller
Shaping the BMP Morphogen Gradient—a quantitative approach
Joe Zinski, Ye Bu, Wei Duo, David Umulis and Mary Mullins
The first formed tooth of the dental row acts as an initiator tooth in zebrafish
Yann Gibert, E. Samarut, M.K. Ellis, V. Laudet
Stem cells and regeneration I
Chair: Jochen Wittbrodt
4th July (Tuesday) 11:00-12:30
How to make a stem cell: novel roles for TGFβ in the haemogenic endothelium
Rui Monteiro, Philip Pinheiro, Nicola Joseph, Tessa Peterkin, Jana Koth, Emmanouela Repapi, Florian Bonkhofer, Arif Kirmizitas, Roger Patient
Notch3 signaling and neural stem cells homeostasis in the adult zebrafish pallium
E. Than-Trong, S. Ortica, L. Bally-Cuif and Alessandro Alunni
Sclerotome Contributes to the Hematopoietic Stem Cell Specification Niche
Clair M. Kelley, N.O. Glenn, D. Gays, Z. Jiang, R.N. Wilkinson, M.M. Santoro, W.K. Clements
SOX2 regulates Müller glia reprogramming and proliferation in the damaged zebrafish retina
David R. Hyde, Ryne A. Gorsuch, Manuela Lahne, Clare E. Yarka and Michael E. Petravick
The Stem Cell Rationale of Permanent Growth
L. Centanin, J. Stolper, E. Ambrosio
Zebrafish heart regeneration depends on alleviation of cardiomyocyte genomic stress by BMP signaling
Mohan Dalvoy, Chi-Chung Wu, Gilbert Weidinger
Stem cells and regeneration II
Chair: Kenneth Poss
4th July (Tuesday) 16:00-17:30
Collagen XIV as a new regulator of basement membrane biomechanics during zebrafish caudal fin regeneration
P. Nauroy, J. Chlasta, A. Guiraud, M. Malbouyres, B. Gillet, E. Lambert, M. Grammont, S. Hughes, Florence Ruggiero
Fndc3a regulates fin development and regeneration in zebrafish through actinotrichia fiber assembly
Daniel Liedtke, Melanie Orth, Isabell Köblitz, Sinje Geuer, Eva Klopocki
Stat3-dependent mitochondrial DNA transcription drives stem cells proliferation in zebrafish
Margherita Peron, Andrea Vettori, Laura Martorano, Francesco Argenton
Stem cell clonal drift regulates adult myotome formation
Phong D. Nguyen, Carmen Sonntag, David B. Gurevich, Lucy Hersey, Sara Alaei, Hieu T. Nim, Ashley Siegel, Thomas E. Hall, Fernando J. Rossello, Sarah E. Boyd, Jose M. Polo, Peter D. Currie
The AhR pathway regulates restorative neurogenesis
Tamara Durovic, R. Di Giaimo, M. Reiser , A. Kociaj, M. Irmler, F. Cernilogar, G. Schotta, J. Barbosa, D. Trümbach, S. Sirko, E. V. Baumgart, J. Beckers, W. Wurst, M. Götz and J. Ninkovic
Wnt signaling controls a pro-regenerative extracellular matrix in functional spinal cord regeneration
Daniel Wehner, T.M. Tsarouchas, A. Michael, C. Haase, G. Weidinger, M.M. Reimer, T. Becker, C.G. Becker
Tissue dynamics
Chair: Francesca Peri
6th July (Thursday) 14:00-16:00
Endothelial actin dynamics during blood vessel morphogenesis
Li-Kun Phng
Neural stem cells dictate shape of the fish eye in a model of continuous organ growth
Erika Tsingos, B. Höckendorf, T. Sütterlin, S. Kirchmaier, N. Grabe, L. Centanin, J. Wittbrodt
Pitx2c orchestrates vertebrate axis extension via mesendodermal cell migration and oriented cell division
Michelle M. Collins, Hans Martin Maischein, Pascale Dufourcq, Patrick Blader, Didier Y.R. Stainier
Planar cell polarity pathway links mechanosensitive feedback between cardiac remodelling and muscle differentiation
M. Swinarski, A.M. Merks, A.M. Meyer and Daniela Panáková
Plasticity & robustness in Siamese zebrafish gastrulation
Antonio C. Ortiz and Nadine Peyriéras
The brain under surveillance: the role neuronal-microglial interactions in the development and repair of the CNS
Francesca Peri
Tissue formation and structure
Chair: Alex Schier
3rd July (Monday) 16:00-17:00
Actin dependent mechanisms for apical interkinetic nuclear migration vary depending on tissue architecture
I. Yanakieva, A. Erzberger, G. Salbreux, Caren Norden
Confined Primed Conversion and Beyond: Generating labels for advanced in vivo imaging
Manuel A. Mohr, Lluc Rullan Sabater, Hanyu Qin, Maaike Welling, Periklis Pantazis
Instruction of chordoblasts by retinoic acid is required for segmental notochord sheath ossification during zebrafish vertebral column development
Hans-Martin Pogoda, L. Schneiders, I. Riedl-Quinkerts, J.D. Waxman, R. Dale, Lleras-Forero, L.S. Schulte-Merker and M. Hammerschmidt
Mechanisms of yolk syncytial layer formation
Zoltán Spiró and Carl-Philipp Heisenberg
Toxicology
Chair: Thomas Dickmeis
6th July (Thursday) 14:00-16:00
Altered Adipogenesis in Zebrafish Larvae Following High Fat Diet and Chemical Exposure is Visualised by Stimulated Raman Scattering Microscopy
Marjo J. den Broeder, Miriam J. B. Moester, Jorke H. Kamstra, Peter H. Cenijn, Valentina Davidoiu, Leonie M. Kamminga, Freek Ariese, Johannes F. de Boer, Juliette Legler
Cell Imaging Counting as a Novel Ex Vivo Approach for Investigating Drug-Induced Hepatotoxicity in Zebrafish Larvae
X-B. Nguyen, S. Kislyuk, D-H. Pham, A. Kecskés, J. Maes, D. Cabooter, P. Annaert, P. A. M. de Witte and Annelii Ny
Characterization of zebrafish organic cation transporter 1 (Oct1) active site(s) and interaction with endo- and xenobiotics
Ivan Mihaljevic, M. Popovic, N. Marakovic, T. Smital
The influence of Bisphenol A exposure on lipid usage during embryogenesis
Prusothman Yoganantharajah, A.C. Ward, P.J. Meikle, A.J. Sinclair and Y. Gibert
Use of several zebrafish-based bioassays to study the mechanisms of action and tissue-specific effects of ligands of the progesterone receptor
Clementine Garoche, O. Kah, S. Aït-Aïssa, N. Creusot, N. Hinfray, P. Balaguer, T. Dickmeis, F. Brion
Using zebrafish to investigate molecular changes after exposure to persistent organic pollutants – from mixture to transgenerational effects of chemicals
Melanie Blanc, S. Alfonso, M.L. Bégout, L. Joassard, N. Scherbak, X. Cousin, S.H. Keiter
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